![]() All symptoms of cardiovascular disease were documented during the examination.Ī standard 12-lead ECG was recorded with the subject at rest using a paper speed of 50 mm/s (standard paper speed in Finland) and a calibration of 1 mV per 10 mm. A specially trained nurse then checked the questionnaire to make sure all the questions were answered appropriately. The subjects also completed a questionnaire regarding their health habits, medication, and known diseases or illnesses. 9 Briefly, in addition to having a standard 12-lead ECG taken, blood pressure, body mass index, and serum cholesterol were measured. Thus, our final study group included 10 899 subjects (52% of whom were men mean age 44.0☘.5 years) from the original cohort.Ī detailed account of the study rationale and procedures performed at the baseline examination has been provided previously. The study cohort comprises a total of 10 957 subjects between the ages of 30 and 59 years, but we excluded 58 ECGs that had missing data or were otherwise unreadable. ![]() The CHD Study was part of a large, prospective Mobile Clinic Health Survey, which was conducted in 35 populations from different geographic areas of Finland representative of the middle-aged Finnish population. ![]() The study population consists of subjects in the Finnish Social Insurance Institution's Coronary Heart Disease Study (CHD Study) who had undergone clinical baseline examinations between 19. Left bundle-branch block also weakly predicted arrhythmic death ( P=0.04), but right bundle-branch block was not associated with increased mortality. Subjects with intraventricular conduction delay had increased all-cause mortality (RR 2.01 CI 1.52–2.66 P<0.001), increased cardiac mortality (RR 2.53 CI 1.64–3.90 P<0.001), and an elevated risk of arrhythmic death (RR 3.11 CI 1.74–5.54 P=0.001). Prolonged QRS duration predicted all-cause mortality (multivariate-adjusted relative risk 1.48 95% confidence interval 1.22–1.81 P<0.001), cardiac mortality (RR 1.94 CI 1.44–2.63 P<0.001), and sudden arrhythmic death (RR 2.14 CI 1.38–3.33 P=0.002). QRS duration ≥110 ms was present in 1.3% (n=147) and intraventricular conduction delay in 0.6% (n=67) of the subjects. Prolonged QRS duration was defined as QRS ≥110 ms and intraventricular conduction delay as QRS ≥110 ms, without the criteria of complete or incomplete bundle-branch block. Primary end points were all-cause mortality, cardiac mortality, and arrhythmic death. ![]() We evaluated the 12-lead ECGs of 10 899 Finnish middle-aged subjects from the general population (52% of whom were men mean age 44☘.5 years) between 19 and followed them for 30☑1 years. Customer Service and Ordering Information.About Circ: Arrhythmia and Electrophysiology.Stroke: Vascular and Interventional Neurology.Journal of the American Heart Association (JAHA).Circ: Cardiovascular Quality & Outcomes.Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB). ![]()
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